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Guggul comes from the resin of the guggul tree. It has been used in Ayurvedic medicine for centuries. Studies suggest that guggulsterone, a chemical found in Guggul helps reduce cholesterol levels. Other uses of Guggul include treating joint pain, arthritis, acne, hardening of the arteries (atherosclerosis), osteoarthritis, urinary tract disorders, reduce triglycerides in the blood (hypertriglyceridemia) and promote weight loss.